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| Ralph B. Puchalski 3D reconstruction of gene expression in brain for Man1a. It was computationally reconstructed 3D rendering of a mouse brain illustrating where one gene (Man1a) is expressed, or turned on. The translucent forms represent the left half of the brain. The spheres show where in the brain the gene is turned on, and the color of the dots reflect the level at which it is turned on. The large red arc indicates that this gene is turned on strongly in the ippocampus, a part of the brain known to be involved in learning and memory. Image was generated from the Allen Brain Atlas (www.brain-map.org) using Brain Explorer. Courtesy of the Allen Institute for Brain Research.itute for Brain Science. |
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| Dale Telgenhoff DFB Branded Pharmaceuticals, Fort Worth, TX Keratinocytes stained and visualized
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| Luis Benitez-Bribiesca, Oncological Research Unit, National Medical Center, Mexico National Medical Center, Mexico Lymphocytes subjected to single cell gel electrophoresis (comet assay) and photographed using a confocal scanning microscope. Stained with acridine orange. The green fluorescent comet corresponds to double strand breaks, the red comet shows single strand breaks, and the lower figure is a combination of green and red fragments. Dots in the tails correspond to fragments of DNA (Reference J. Histochem. Cytochem. 49: 921-922, 2001). |
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| Helen
Gruber Dept. Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC Polarized microscopy view of cortical bone. |
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Allen Gown PhenoPath, Inc. Seattle, WA |
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| Richard Levenson CRI, Inc., Boston, MA Brightfield immuncytochemistry image of lymph node with metastatic cancer (red) and T cells (green) (node sample courtesy of Peter Lee, Stanford University). |
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| Ann
Dvorak Dept. Pathology, Beth Israel Deaconess Medical Center, Boston, MA Mouse skin venule. Interconnected collections of vesicles and vacuoles (termed vesicle-vacuolar organelle) (open arrowhead) populate two endothelial cells which are connected by their lateral borders and tight junction (arrow) at their lumenal ends. L=lumen, R=RBC. Note: numerous membrane-attached caveolae in the pericyte. Photograph courtesy of TE Sciuto and AM Dvorak, Depts of Pathology,
Beth Israel Deaconess Medical Center and Harvard Medical School, Boston,
MA. |
